Nicotine

• There is no safe level of drug use. Use of any drug always carries some risk. It’s important to be careful when taking any type of drug.
• Nicotine affects everyone differently, based on:
  • size, weight and health
  • whether the person is used to taking it
  • whether other drugs are taken around the same time
  • the amount taken
  • the strength of the tobacco and how much is contained in the product.
• The following effects may be experienced among people who do not normally smoke tobacco products:
  • dizziness
  • headache
  • nausea
  • abdominal cramps
  • possibly vomiting or weakness
  • For people who smoke tobacco products regularly, they will build up a tolerance to the immediate short-term effects of smoking tobacco, and may experience the following effects after smoking:
  • mild stimulation
  • increase in heart rate
  • increased ability to concentrate
  • relaxation
  • temporary reduction in the urge to smoke
  • coughing
  • dizziness, headaches
  • bad breath
  • tingling and numbness in fingers and toes
  • reduced appetite, stomach cramps and vomiting.
  • If a large amount of nicotine is taken the following effects may also be experienced:
  • confusion
  • feeling faint
  • seizures
  • fast breathing
  • respiratory arrest (stop breathing) and death
  • Some people believe that smoking ‘light’ or ‘low tar’ cigarettes is less harmful than regular cigarettes. However, there is little difference between the amount of chemicals inhaled by people who smoke ‘light’ cigarettes and those who smoke regular ones

Long-term effects

Use of nicotine through smoking may eventually cause the following types of chronic disease and issues:

• stroke
• blindness, cataracts (eye diseases)
• birth defects if the fetus is exposed to cigarettes
• periodontitis (yellowing teeth, gum disease)
• aortic aneurism (enlarging of major blood vessels)
• coronary heart disease
• pneumonia
• various respiratory diseases (shortness of breath, asthma, coughing fits)
• diabetes
• reduced fertility
• ectopic pregnancy (in the fallopian tube)
• hip fractures
• male sexual dysfunction
• rheumatoid arthritis
• reduced immune function (regular colds and flu)
• overall diminished health (ageing, back pain, slower healing wounds, mood swings)
• dependence on smoking
• financial, work and social problems.
• Smoking cigarettes containing nicotine are causally linked to the following cancers (i.e. smoking may directly cause these cancers)
  • oropharynx
  • larynx
  • oesophagus
  • trachea, bronchus and lung
  • acute myeloid leukemia
  • stomach
  • liver
  • pancreas
  • kidney and ureter
  • cervix
  • bladder
  • colorectal.

Using nicotine with other drugs

• The effects of using nicotine with other drugs – including over-the-counter or prescribed medications – can be unpredictable and could cause:
• Nicotine + benzodiazepines: reduced effectiveness of benzodiazepines.
• Nicotine + contraceptive pill: increased risk of blood clots forming
• Smoking tobacco appears to increase the amount of Warfarin (a prescribed medication) required to be effective
• It’s important to check with a medical professional about whether nicotine might affect any medications you are taking.

Withdrawal

Giving up nicotine after using it for a long time is challenging because the body has to get used to functioning without it. Withdrawal symptoms usually start within 2–3 hours after you last use tobacco. The symptoms may last from a few days to a few weeks. These symptoms can include:

• cravings
• irritability, anxiety and depression
• restless sleep
• eating more and putting on weight
• trouble concentrating
• headaches
• coughing and sore throat
• aches and pains
• upset stomach and bowels