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DVT
management is from eTG 2024 Definition and Types Clinical Significance Symptoms Risk Factors Diagnosis of VTE Clinical Prediction Tools Diagnostic Imaging Treatment of VTE Anticoagulant Therapy Suggested duration of anticoagulant therapy to treat acute venous thromboembolism Clinical situation Duration of therapy Proximal DVT or PE that was unprovoked or associated…
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Macrocytic Anemia
Definition Classification Epidemiology Etiology Pathophysiology Histopathology Clinical Presentation Evaluation Treatment and Management Prognosis and Complications Differential Diagnosis Patient Education Key Points
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Polycythemia
Overview Hemoglobin and Hematocrit Standards Polycythemia Etiology and Classification Spurious Polycythemia – Relative (reduced plasma volume) True Polycythemia – Absolute (increase in red cell mass) Based on Serum Erythropoietin (EPO) Levels: Neonatal Polycythemia Polycythemia Vera (PV) Epidemiology Pathophysiology Histopathology Clinical Presentation History Physical Examination Evaluation Upfront investigations Selective investigations dependent…
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Leukaemia
General Information Age Ranges Acute Leukaemia Symptoms Signs Diagnosis Treatment Note: Relapse of acute leukaemia often means imminent death unless bone marrow transplantation is successful. Mean 5-year survival rate: Chronic Myeloid Leukaemia (CML) Clinical Features Chronic Lymphocytic Leukaemia (CLL) Clinical Features Note: Most cases, especially early indolent CLL, require no…
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Bleeding Disorders
General Presentation Key facts and checkpoints Purpura Bruises Differential Diagnosis THE CLINICAL APPROACH History Indicators of Systemic Bleeding Defect Diagnostic Tips Family History Key Questions Medication Record Examination and Investigations Skin Examination Initial Investigations Abnormal Bleeding in Children Common Conditions Infective States Abnormal Bleeding in Older Adults Platelet Disorders Features…
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Anticoagulation in Pregnancy for DVT/PE
First-line Therapy: Low Molecular Weight Heparin (LMWH) Unfractionated Heparin (UFH) Fondaparinux Warfarin Monitoring and Adjustment Peripartum Management Summary
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B12 deficiency
DDx: Ix: Mx: Physiology of Vitamin B12 B12 Functional Roles Normal B12 Absorption Pathway Vitamin B12 Storage Clinical Manifestations of Vitamin B12 Deficiency
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Lymphoma
Comparison of Hodgkin and Non-Hodgkin Lymphoma Aspect Hodgkin Lymphoma malaise + fever/night sweats + pruritus → Hodgkin lymphoma Non-Hodgkin Lymphoma malaise + fever/night sweats + lymphadenopathy → non-Hodgkin lymphoma Classification Malignant tumor of lymphoid tissue Heterogeneous group of cancers of lymphocytes (B or T cells) Lymphadenopathy Painless, rubbery, especially cervical nodes Painless, localized or…
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Thalassemia
Hemoglobin Types Alpha Thalassemia Variant Chromosome 16 Signs and symptoms Alpha thalassemia silent carrier One of four gene deletions Asymptomatic Alpha thalassemia trait Two of four gene deletions Asymptomatic Hemoglobin Constant Spring Reduced output of alpha globin Silent or mildly symptomatic Alpha thalassemia intermedia with significant hemoglobin H (hemoglobin H…
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Anaemia in pregnancy
AJGP Anaemia in pregnancy – https://www1.racgp.org.au/ajgp/2019/march/anaemia definition known risk factors Interpretation of pathology results Treatment recommendations of iron deficiency Supplement name Iron content Elemental iron content Ferro-Grad C Ferrous sulfate 325 mg 105 mg Ferro-Gradumet Ferrous sulfate 325 mg 105 mg Maltofer tablets Iron polymaltose 370 mg 100 mg Maltofer syrup…