• PAEDIATRICS,  RESPIRATORY,  RESPIRATORY PEADS

    Asthma – child aged 1–5 years

    gathered from https://www.asthmahandbook.org.au/ -v2.0 Asthma in children is defined clinically as a combination of variable respiratory symptoms (e.g., wheeze, shortness of breath, cough, and chest tightness) and excessive variation in lung function, which indicates variable airflow limitation greater than that seen in healthy children. Key Points Age-specific Diagnostic Considerations Infants…

  • PAEDIATRICS,  RESPIRATORY,  RESPIRATORY PEADS

    Asthma – likelyhood

    gathered from https://www.asthmahandbook.org.au/ -v2.0 Checking Whether Current Symptoms Are Due to Asthma Recommendations Likelihood of Asthma Asthma More Likely Criteria Details Symptoms More than one of wheeze, breathlessness, chest tightness, cough Symptom Pattern Recurrent or seasonal, worse at night or early morning History of Allergies Allergic rhinitis, atopic dermatitis Triggers…

  • RESPIRATORY

    Restrictive lung diseases

    Definition and Characteristics: Classification of Causes: Causes of pulmonary fibrosis can be divided into those that affect the upper lobes and those predominantly affecting the lower lobes Upper lobes (SCHART-S) Lower lobes (RASCO) Epidemiology Prevalence: Difficult to estimate precisely due to multiple pathological conditions, but up to 3-6 cases per…

  • RESPIRATORY

    Upper Respiratory Tract Infection (URTI)

    Introduction: Etiology: Risk Factors: Pathophysiology: Influenza: Common Cold: Differentials History and Physical: Evaluation: Treatment/Management: Prevention/reduce transmission Vaccination (see influenza vaccine) Antiviral Prophylaxis Prognosis:

  • RESPIRATORY

    Pulmonary Function Tests

    Flow Volume Loops, before and after bronchodilator Flow volume loops (FVL) are critical in pulmonary function testing, providing a graphical representation of airflow versus volume over time. Below are the key aspects of FVL, both before and after bronchodilator administration: Before Bronchodilator: After Bronchodilator: Additional Considerations: Flow volume loops provide…

  • RESPIRATORY

    Lung Function Test results

    Normal Results Definition: All measured parameters are within the normal range and FEV1/FVC ratio is > 0.70 Possible Intervention: Review patient in 12 months following repeat spirometry Obstructive Pattern Definition: FEV1/FVC ratio is ≤ 0.70 Severity based on post-FEV1 percent predicted (as per ATS/ERS guidelines) COPD or chronic asthma should be considered…

  • PAEDIATRICS,  RESPIRATORY,  RESPIRATORY PEADS

    Pertussis / Whooping Cough 

    Assessment Catarrhal Phase (1-2 weeks, sometimes as short as a few days in infants <3 months) Paroxysmal Cough Stage (2-4 weeks with a peak at 2 weeks, may persist up to 10 weeks) Recovery Phase Complications Investigations Management Prophylaxis Recommended antibiotic for post-exposure prophylaxis for pertussis – Australian Prescriber – VOLUME…

  • ENT,  INFECTIOUS DISEASES,  NOSE,  RESPIRATORY

    Sinusitis

    Overview: Prevalence: Anatomy: Paranasal Sinuses: Mucociliary System: Pathophysiology: Diagnostic criteria (from the European Position Paper on Rhinosinusitis) Adult Acute Rhinosinusitis: Adult Chronic Rhinosinusitis: Paediatric Acute Rhinosinusitis: Paediatric Chronic Rhinosinusitis: Acute rhinosinusitis (ARS) Clinical assessment The signs and symptoms of acute viral and bacterial rhinosinusitis overlap considerably, especially during the first 3…

  • ENT,  IMMUNOLOGY,  NOSE,  RESPIRATORY

    Allergic Rhinitis

    Rhinitis, also known as coryza, is irritation and inflammation of the mucous membrane inside the nose. Common symptoms are a stuffy nose, runny nose, sneezing, and post-nasal drip. Differentials: Differential Diagnosis: Mechanism of Allergic Rhinitis: Epidemiology: Clinical Impact: Risk/Protective Factors: classification While this classification is useful for specific treatments such…

  • ENT,  INFECTIOUS DISEASES,  INFECTIOUS DISEASES PAEDS,  RESPIRATORY

    Peritonsillar abscess (quinsy) 

    Epidemiology Pathophysiology Symptoms Physical Exam Findings Clinical features associated with airway obstruction or deep neck space infection Conditions associated with airway obstruction or deep neck space infection Initial Management:  Abscess drainage Antibiotics          OR continue intravenous therapy for 1 to 2 days following successful abscess drainage, then switch oral therapy Antibiotics…

  • ENT,  INFECTIOUS DISEASES,  RESPIRATORY

    Glandular fever (EBV)

    clinical features of acute EBV infection Adolescent infectious mononucleosis Clinical Status IgM VCA(<36)* IgG VCA(<18)* Anti-EA(<9)* Anti-EBNA(<18)* Susceptible Negative Negative Negative Negative Acute Primary Infection Positive Positive Positive Neg/Wk Pos Recent Primary Infection Neg/Wk Pos Positive Positive Positive Past Infection Negative Positive Negative Positive Reactivation in Immunosuppressed orImmunocompromised Individuals Negative…

  • RESPIRATORY

    Pulmonary embolus 

    Types Common clinical features of pulmonary embolism RISK FACTORS Major (relative risk 5-20) – SLOMMP Moderate risk factors (odds radio 2–9) Weak risk factors (odds ratio <2) Thrombophillias INVESTIGATIONS PERC rule The PERC rule validation study included patients who presented with a primary complaint of shortness of breath or chest…

  • RESPIRATORY

    Pneumothorax 

    Pneumothorax Classification Primary Spontaneous Pneumothorax (PSP) Secondary Pneumothorax Symptoms Signs CXR Findings Management Large Pneumothorax Collin’s Method (see image below)- A+B+C > 6cm Management Guidelines for Spontaneous Pneumothorax General Approach Specific Patient Management Follow-Up and Monitoring Surgical Consultation Considerations Regarding Air Travel

  • RESPIRATORY

    Systemic Diseases Involving Lung

    “Collagen-vascular” or “connective tissue” diseases commonly involve lung and typically cause interstitial lung disease. SYSTEMIC LUPUS ERYTHEMATOSUS Pleural lesions  Parenchymal lesions RHEUMATOID ARTHRITIS Pleural lesions  Parenchymal lesions PROGRESSIVE SYSTEMIC SCLEROSIS (SCLERODERMA) OTHERS

  • RESPIRATORY

    Sarcoidosis 

    Etiology Epidemiology Pathophysiology Histopathology History and Physical Evaluation Treatment / Management Differential Diagnosis Prognosis Complications

  • RESPIRATORY

    Asbestos-related

    THERE ARE SEVERAL DIFFERENT DISEASES RELATED TO ASBESTOS EXPOSURE 1. Asbestosis 2. Pleural plaques: 3. Asbestos related pleurisy and pleural effusions 4. Pleural thickening 5. Asbestos related lung cancer 6. Mesothelioma Exposure CXR Lung function Symptoms Outcome Asbestos bodies Light Normal Normal None Evidence of asbestos exposure only Pleural plaques…

  • RESPIRATORY

    Pneumoconiosis 

    “dust diseases” – non neoplastic reaction of lungs to inhaled mineral or organic dust The reaction of the lung depends on: Inert dusts → interstitial aggregates of dust-filled macrophages (DUST MACULE) Fibrogenic dusts → hyaline nodules or stellate areas of fibrosis, peribronchiolar fibrosis, diffuse interstitial fibrosis +/- granulomas and large…

  • RESPIRATORY

    Interstitial lung diseases (ILDs) 

    affect the lung interstitium, i.e. the space between the alveolar epithelium and the capillary endothelium, causing inflammation and fibrosis. ILD refers to over 200+ disease entities which share a common pathological process. The interstitium is damaged, leading to progressive pulmonary fibrosis Aetiology main types: Causes of pulmonary fibrosis can be…

  • RESPIRATORY

    Lung Abscess

    Definition: Severe localised suppuration of lung associated with cavity formation on CXR (often with a fluid level) and NOT due to TB. Causes: Suppurative thromboembolism(eg, septic embolism from IV drug use)Right-sided endocarditis 🡪 hematogenous seeding of the lungs  🡪 necrotizing pneumonia 🡪 Abscess(may result in multiple lung abscesses) Pathogens:  Noninfectious…

  • RESPIRATORY

    ALTITUDE AND LUNG DISEASE

    Disorders associated with altitude can happen in healthy travellers, usually after rapid ascent to at least 2500m above sea level. Potentially fatal. Can be given prophylactic meds acetazolamide, dexa and nifedipine: ALTITUDE AND OSA

  • RESPIRATORY

    Tuberculosis

    Etiology: Epidemiology in Australia: Transmission: Risk Factors for Infection: Risk Factors for Progression to Disease: Populations at Increased Risk: GPs Role in TB Management:   Tuberculosis (TB) Clinical Overview Primary TB Pathophysiology Post-primary TB (Reactivation TB) Progressive Primary TB with bronchial spread:– granulomatous bronchopneumonia– endobronchial TB– laryngeal TB   with lymphatic-haematogenous…

  • RESPIRATORY

    COPD

    Definition Risk factors Symptoms and Signs Investigations (https://www.safetyandquality.gov.au/standards/clinical-care-standards/chronic-obstructive-pulmonary-disease-clinical-care-standard/information-clinicians) Pharmacological Management Step 1: Initial Management with Short-Acting Bronchodilators Step 2: Persistent Symptoms – Long-Acting Bronchodilator Step 3: Dual Long-Acting Bronchodilator Therapy Step 4: Addition of Inhaled Corticosteroids (ICS) Step 5: Macrolide Antibiotics (for Selected Patients) Inhaler and Spacer Technique Acute Exacerbations…

  • RESPIRATORY

    Spirometry

    Recommendations for Spirometry Asthma Indications for Spirometry: COPD Indications for Spirometry: Abbreviation  Name Definition Notes FVC (litres) Forced vital capacity The maximum volume of air that can be expired during a single expiratory manoeuvre using maximal effort initiated following a full inspiration Indicates lung capacityFVC compared with LLN is used to…

  • RESPIRATORY

    Bronchietasis

    defined as a pathological diagnosis typically confirmed by radiology. Defined as irreversible abnormal dilatation of the bronchial tree. It has a variety of underlying causes, with a common etiology of chronic inflammation. due to injury to the airways, which is typically associated with chronic and recurrent inflammation because of an…

  • RESPIRATORY

    Aspiration Pneumonia

    Aspiration Pneumonia  AUGUST 12, 2023 RESPIRATORY 0 COMMENTS Term Definition Is antibiotic therapy required? Aspiration       The inhalation of foreign material (eg food, vomit, blood, saliva) into the lungs. Predisposing:– Impaired consciousness eg due to: trauma, stroke, general anaesthetic,seizure, overdose, alcohol or drug intoxication– Esophageal dysmotility– Post-bronchial obstruction– Gum disease– neurological disorders NoMonitor…

  • PAEDIATRICS,  RESP DDx,  RESPIRATORY

    Stridor Differentials

     Stridor:   History Examination Age Frequency Tests Management Croup Associated URTI Barking cough +/ fever, not toxic high pitched stridor 6 m6y mean 18m Common Nil Supportive Steroids Adrenaline Epiglottitis Sudden onset Rapid progression No preceding cough URTI 2550% Sitting up Toxic, pale, drooling Low pitched stridor 90% 2yr Rare…

  • PAEDIATRICS,  RESPIRATORY

    Bronchiolitis

    Overview VIRAL INFLAMMATION OF THE BRONCHIOLES produces small airway obstruction with air trapping and respiratory difficulty in infants  Age: 0-1 years An infant or child less than 18 months of age presenting with initial symptoms and signs of upper respiratory tract infection followed by cough, tachypnoea, inspiratory crepitations and wheeze…

  • PAEDIATRICS,  RESPIRATORY

    Coughing, Wheezy and Stridulous Children

    LRTI vs URTI – Key Learning Points Pneumonia in Children (LRTI) URTI in Children Wheeze in Children Bronchiolitis in Children Case Example: Perplexing Case – A Wheezy 6-week-old Viral Wheeze in Children Understanding the distinctions between bronchiolitis and viral wheeze is essential for appropriate management and treatment to ensure the…

  • RESPIRATORY

    Pneumonia

    Overlapping Signs and Symptoms of Pneumonia and Acute Bronchitis Pneumonia and acute bronchitis share similar clinical features: Diagnosing Pneumonia in Patients with COPD or Bronchiectasis The symptoms of pneumonia often overlap with those of COPD and bronchiectasis, making accurate diagnosis crucial, as the treatment for exacerbations differs from pneumonia management.…

  • RESPIRATORY

    Protracted Bacterial Bronchitis In Children

    Is an infective cause of chronic wet cough lasting longer than 4 weeks in children. Occurs in <5 years of age If the child has a dry cough, this excludes the diagnosis of protracted bacterial bronchitis. Evidence suggests that PBB may be a common enough condition to warrant its inclusion…

  • RESPIRATORY

    Acute Bronchitis

    self-limiting lower respiratory tract infection, most common cause of cough in the general practice setting. definition:  Acute cough (productive or nonproductive) +  signs of a lower respiratory tract infection Sputum production Dyspnoea Wheeze Chest discomfort less than 14 days duration There should be no other obvious cause, eg. asthma, sinusitis,…

  • RESP DDx,  RESPIRATORY

    Dyspnoea

    Airways disease Chronic bronchitis and emphysema Asthma Bronchiectasis Cystic fibrosis Laryngeal or pharyngeal tumour Bilateral cord palsy Tracheal obstruction or stenosis Tracheomalacia Crico-arytenoid rheumatoid arthritis Parenchymal disease Pneumonia Allergic alveolitis Sarcoidosis Fibrosis and diffuse alveolitis Diffuse infections Respiratory distress syndrome Infiltrative and metastatic tumour Pneumothorax Pneumoconiosis Pulmonary circulation Pulmonary embolism…

  • RESP DDx,  RESPIRATORY

    cough

    Most likely: Not to be missed: Spasmodic Cough, Paroxysmal cough, Coughing Fits Often missed: Masquerade:  Drugs eg. ACEi, β blockers, inhaled steroids Hidden agenda: Anxiety Causes by age group Paediatric Adolescent/ YA Middle age Elderly RefluxAsthmaURTI/ CroupBronchitisPertussisCFCroupFB inhalationPneumonia AsthmaPsychogenicSmoking Infection Smoking/Irritants GORDLung cancerDrugsAnxiety InfectionCOPDLung cancerDrugs