DERMATOLOGY,  PRURITIS

Prurigo nodularis / Nodular prurigo

  • These are extremely pruritic firm lumps about 1– mm in diameter that erupt on the arms, legs and trunk. They can affect all ages and may manifest in late pregnancy. 
  • Scratching leads to:
    1. Enlargement resulting in a nodular, raised, warty surface
    2. Nodules tend to be firm and small but can measure up to 3 cm in diameter
    3. Older nodules are normally darker and are surrounded by paler, dry skin
    4. Nodules are grouped and follow a symmetrical distribution
    5. Some may ulcerate increasing infection risk
    6. Healed lesions can leave a scar or discolouration
  • Definite diagnosis is with skin biopsy. 
  • They tend to run a long course and are difficult to treat.

DDx

  •     Atopic dermatitis
  •     Pemphigoid nodularis
  •     Nodular scabies
  •     Multiple keratoacanthomas
  •     Reactive perforating collagenosis

Mx

  • Topical steroid cream or ointment
  • stops scratching the lesions, as this can make the condition worse.
  • Strategies that can help include:
    • Keeping your mind busy
    • Cooling the affected areas: Laying a cool flannel on the skin may reduce inflammation and help ease the itching
    • some people keep flannels in the fridge for this purpose

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