EYE,  VISION LOSS

Presbyopia

  • Prevalence: Presbyopia is a leading cause of visual impairment for near vision in older adults.
  • Global Impact: Affects over a billion people worldwide.
  • Regional Data: In the Brazilian Amazon region, presbyopia accounted for 71.8% of near visual impairment cases.

Etiology

  • Cause: Progressive decrease in the accommodative capacity of the lens.
  • Theories:
    • Helmholtz’s Theory: Ciliary muscle contraction leads to relaxation of zonules and increased convexity of the anterior lens capsule.
    • Schachar’s Theory: Ciliary muscle contraction increases tension in equatorial zonular fibers and relaxes anterior and posterior zonular fibers, resulting in lens shape changes.
    • Catenary Theory of Coleman: Ciliary muscle contraction creates a pressure gradient from vitreous to aqueous compartments, steepening the anterior lens capsule.

Epidemiology

  • Age of Onset: Around 40 years.
  • Economic Impact: Affects the most economically active age group.
  • Presbyopia Correction Rates: Low in developing nations due to lack of awareness and affordability; even in developed countries, many do not use corrective lenses.
  • Statistical Data: Near visual impairment noted in 13.6% (US study) and 21.6% among non-indigenous and 34.7% among indigenous Australians (Australian National Eye Health Survey).

Pathophysiology

  • Mechanism: Increased stiffness of the crystalline lens.
  • Clinical Manifestation: Difficulty reading at the usual distance.
  • Age-Related Changes: Equal stiffness of lens nucleus and cortex around 35-40 years.

History and Physical Examination

  • Symptoms: Difficulty reading fine print, headaches, delayed focusing, squinting, drowsiness during near work, and need for bright light.
  • Evaluation Tools: Royal Air Force (RAF) rule to calculate near point of accommodation (NPA).

Evaluation

  • Method: Subjective evaluation using reading targets and lens adjustments to determine dioptric power needed.

Treatment / Management

Non-surgical Options:

  1. Spectacles:
    • Single Vision Lenses: Cheaper, for near vision only.
    • Bifocal Lenses: Corrects for near and distance vision.
    • Progressive Lenses: Corrects near, intermediate, and distance vision; more expensive.
  2. Contact Lenses:
    • Monovision: Corrects one eye for distance, the other for near.
    • Multifocal Contact Lenses: Corrects near, intermediate, and distance vision.

Surgical Options:

  1. Corneal Procedures:
    • Monovision with Laser Refractive Correction: Effective but may affect vision quality.
    • Conductive Keratoplasty: Corneal collagen shrinkage increases refractive power.
    • Intracorneal Inlays: Devices like Kamra inlay increase depth of focus.
  2. Scleral Procedures:
    • Scleral Expansion: Implants to restore ciliary muscle function (insufficient data).
  3. Intraocular Implants:
    • Phakic Intraocular Lenses: Corrects near and distance vision.
    • Clear Lens Extraction: Followed by intraocular lens (IOL) implantation.
    • Multifocal and Trifocal IOLs: Better visual acuity at intermediate distances.

Differential Diagnosis

  • Conditions Affecting Near Vision:
    • Macular/retinal diseases
    • Diseases of the optic nerve
    • Posterior subcapsular cataract
    • Hypermetropia
    • Astigmatism

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