PUPPP – pruritic urticarial papules and plaques of pregnancy

• Polymorphic eruption of pregnancy is an itchy, bumpy rash that starts in the stretch marks of the abdomen in the last 3 months of pregnancy then clears with delivery. 
• rash usually begins during the third trimester, in the last few weeks of pregnancy.
• About 15% of women with polymorphic eruption of pregnancy report that it actually began immediately after delivery.

Rx

• Emollients (moisturisers) applied liberally and frequently as required.
• Topical steroids applied thinly once or twice daily to the red itchy patches.
• A short course of systemic steroids (eg, prednisone), in severe polymorphic eruption of pregnancy.
• Antihistamines — antihistamine tablets appear safe in late pregnancy (though they may make the baby drowsy on delivery).