Phobic Disorders
- Phobia: irrational fear of specific objects, places or situations, or activities
- the fear is irrational, excessive & disproportionate to actual danger
3 types of phobias:
- Agoraphobia – fear of being unable to escape a place or situation
- social phobia – fear of humiliation or embarrassment in public places
- specific phobia – isolated phobias
Social phobia
- A marked or persistent > 6 months
- fear of 1/more social or performance situations
- When exposed to unfamiliar people
- Fear of possible scrutiny by others
- having a conversation
- meeting unfamiliar people
- being observed (e.g. – eating or drinking)
- performing in front of others (e.g. – giving a speech).
- will act in a way or show anxiety symptoms that will be negatively evaluated (i.e. – will be humiliating or embarrassing: will lead to rejection or offend others).
- Avoidance
- Feared social or performance situations are avoide
- interferes significantly with person’s
- normal routine
- occupation fx
- social activities or relationships
- Person recognises that the fear is excessive or unreasonable
- not due to
- direct effects of a substance
- general medical condition
- better accounted for by another mental disorder
- If individual is < 18yrs, the duration is at least 6 mths
- Epidemiology:
- Tends to run in families
- DDx:
- Up to 72% of individuals have another psychiatric disorder diagnosis
- Other anxiety disorders
- Mood disorders
- Schizoid & avoidant personality disorders
- Management:
- In performance-type social anxiety disorder
- beta-blockers have been used for performance anxiety
- Cognitive behavioural therapy with exposure
- first-line
- gold-standard treatment for social anxiety disorder.
- 2nd line: pharmacotherapy:
1st line | Monotherapy: escitalopram, fluvoxamine, fluvoxamine CR, paroxetine, paroxetine CR, pregabalin, sertraline, venlafaxine XR |
2nd line | Monotherapy: alprazolam, bromazepam, citalopram, clonazepam, gabapentin, phenelzine |
3rd line | Monotherapy: atomoxetine, bupropion SR, clomipramine, divalproex, duloxetine, fluoxetine, mirtazapine, moclobemide, olanzapine, selegiline, tiagabine, topiramate. |
Adjunctive therapy | Aripiprazole, buspirone, paroxetine, risperidone |
Not recommended | Monotherapy: atenolol*, buspirone, imipramine, levetiracetam, propranolol*, quetiapine Adjunctive therapy: clonazepam, pindolol |
- Beta-blockers
- have been successfully used in clinical practice for performance situations such as public speaking.
- Benzodiazepines
- be used at any time if there is an acute and severe exacerbation of agitation or anxiety in individuals with SAD who do not have co-morbid alcohol or substance abuse.
- should be used as a short term solution only as 1⁄4 of patients with generalized SAD have co-morbid substance use
Agoraphobia
- fear of being unable to escape a place or situation to such an extent that he/she learns to avoid it
- fear of being unable to get help in the event of a panic attack
- Marked fear or anxiety about at least 2 of the following 5 situations:
- Public transportation (e.g. – automobiles, buses, trains, ships, planes)
- Open spaces (e.g. – parking lots, malls, marketplaces, bridges)
- Enclosed places (e.g. – rooms, shops, theatres, cinemas)
- Crowds or standing in line
- Being outside of home alone
- avoids these situations because of thoughts that:
- Escape might be difficult, or
- Help might not be available in the event of developing panic-like symptoms or other incapacitating or embarrassing symptoms (e.g. – fear of falling or fear of incontinence in the elderly).
- the fear, anxiety, or avoidance is persistent, typically lasting for 6 months or more
- Beyond the panic attack symptoms (see above), other incapacitating or embarrassing symptoms include symptoms such as:
- Vomiting and inflammatory bowel symptoms
- In older adults, a fear of falling
- In children, a sense of disorientation and getting los
- Epidemiology
- F > M
- chronic lifelong condition
- attacks fluctuate in frequency, intensity & severity
- Clinical Presentation:
- onset: mid 20s (80% < 30 yrs) – but can being at any age
- usually no precipitating event
- some pts will report onset after significant life event
- initial attack – most pts v alarmed → present to ED
- medical workup – usually –ve
- panic attack:
- sudden onset
- peak within mins
- last 5 – 30mins
- Differential Dx:
- Medical illness
- angina
- cardiac arrhythmias
- congestive heart failure
- hypoglycaemia
- hypoxia
- pulmonary embolism
- severe pain
- thyrotoxicosis
- carcinoid
- pheochromocytoma
- Meniere’s diseasd
- Drugs
- caffeine
- sympathomimetic agents e.g. decongestants
- psychostimulants & hallucinogens
- withdrawal – alcohol & benzos
- thyroid hormones
- antipsychotic meds
- Psychiatric illness
- PTSD
- SCZ
- mood disorders
- personality disorders
- adjustment disorder with anxious mood
- Management:
- Panic attack:
- relaxation techniques – deep breathing or rebreathing into a paper bag
- Panic disorder:
- 1st line – individual psychotherapy
- CBT
- distraction & breathing exs
- help make appropriate attributions to distressing Sx
- ↑ self-esteem
- problem solving
- education re: panic disorder & agoraphobia
- agoraphobia: Exposure therapy
- Panic attack:
- Pharmacotherapy – if CBT is not available or not effective
- 1st line – SSRIs, Venlafaxine (SNRI)
- dosages similar to Tx of depression
- pts should continue meds for at least 6 months – 1 yr to prevent relapse
- 2nd line – TCAs, benzos, irreversible MAOIs
- Avoid caffeine