RENAL

Renal artery stenosis 

  • This condition may result in secondary hypertension and secondary hyperaldosteronism. 
  • Other possible features include:
    • coexistant cerebrovascular, cardiovascular or peripheral vascular disease
    • deterioration of renal function following treatment with ACE inhibitor
    • signs of coexistant vascular disease
      • carotid or femoral bruit
      • abdominal bruit
      • absent peripheral pulses
  • A small kidney will be seen on intravenous urography on the affected side with a delayed and persistent nephrogram
  • Causes
    • atherosclerosis (>90%) in the adult population
    • fibromuscular dysplasia (FMD) –  common in younger female patients
  • Management
    • Fibromuscular dysplasia responds well to balloon dilatation, often resulting in a normal blood pressure.
    • Atherosclerosis may respond to balloon dilatation but the effect on blood pressure is unpredictable
    • If renal artery stenosis is bilateral, balloon dilatation often leads to improved renal function.

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