- This condition may result in secondary hypertension and secondary hyperaldosteronism.
- Other possible features include:
- coexistant cerebrovascular, cardiovascular or peripheral vascular disease
- deterioration of renal function following treatment with ACE inhibitor
- signs of coexistant vascular disease
- carotid or femoral bruit
- abdominal bruit
- absent peripheral pulses
- A small kidney will be seen on intravenous urography on the affected side with a delayed and persistent nephrogram
- Causes
- atherosclerosis (>90%) in the adult population
- fibromuscular dysplasia (FMD) – common in younger female patients
- Management
- Fibromuscular dysplasia responds well to balloon dilatation, often resulting in a normal blood pressure.
- Atherosclerosis may respond to balloon dilatation but the effect on blood pressure is unpredictable
- If renal artery stenosis is bilateral, balloon dilatation often leads to improved renal function.
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