ENT,  IMMUNOLOGY,  NOSE,  RESPIRATORY

Nonallergic Rhinitis

  • The diagnosis of nonallergic rhinitis is made after eliminating allergic or IgE-mediated causes. 
  • The most common cause of nonallergic rhinitis is an acute viral infection. 
  • Less common chronic causes include
    • Vasomotor rhinitis
    • Hormonal rhinitis
      • pregnancy, oral contraceptive use, and hypothyroidism.
      • Pregnancy-induced rhinitis generally improves after delivery. 
      • Symptom improvement after hypothyroidism treatment remains unclear. 
    • Non-allergic rhinitis with eosinophilia syndrome
    • Occupational rhinitis (irritant subtype)
    • Rhinitis medicamentosa
      • Repetitive use of topical alpha-adrenergic decongestant sprays (for five to seven consecutive days) may induce rebound nasal congestion after withdrawal (rhinitis medicamentosa). 
      • Extensive use may cause inflammatory mucosal hypertrophy and chronic congestion. 
      • The mucosa becomes red and inflamed with occasional bleeding. 
      • Discontinuation of the topical decongestant resolves the problem, although many patients find this process difficult
    • Drug-induced rhinitis
      • aspirin
      • oral contraceptive pill
      • ACE inhibitors
      • methyldopa
      • vasoconstrictor nasal sprays

Vasomotor rhinitis

  • is characterized by prominent symptoms of nasal obstruction, rhinorrhea, and congestion. 
  • may be caused by autonomic stimulation 
  • 2 types
    • “Runners,” who demonstrate “wet” rhinorrhea
    • “Dry” patients, who exhibit nasal obstruction and airflow resistance with minimal rhinorrhea
  • These symptoms are excessive at times and are exacerbated by 
    • certain odors (e.g., perfumes, cigarette smoke, paint fumes, inks)
    • alcohol
    • spicy foods (gustatory rhinitis)
    • emotions and sexual arousal
    • environmental factors – temperature, barometric pressure changes, and bright lights.
    • Management

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